Yonago Acta medica 2008;51:21–24
Bilateral Multiple Pulmonary Sclerosing Hemangioma in a Young Male Patient
Kenichiro Miyoshi, Hiroshige Nakamura*, Ken Miwa*, Yoshin Adachi*, Shinji Fujioka*, Yuji Taniguchi* and Yasushi Horie†
Center for Clinical Residency Program, *Division of General Thoracic Surgery and †Pathology Division, Tottori University Hospital, Yonago 683-8504, Japan
The patient was a 24-year-old male who visited our University Hospital complaining of chest pain, and chest computed tomography revealed multiple bilateral nodules. The chest pain disappeared almost immediately, but the tumor underwent no changes during the 3 years of follow-up observations. We used a thoracoscope to perform a partial lung resection of a nodule that reached a maximum diameter of 9 mm for the purpose of obtaining a definite diagnosis. From the pathological findings, the patient was diagnosed to have pulmonary sclerosing hemangioma in which circular tumor cells lacking nuclear atypia rose to papillary hyperplasia. The mindbomb homolog-1 positive rate (MIB-1 index) of the tumor cells was less than 1%, and it is believed to have a poor proliferation activity. Pulmonary sclerosing hemangioma is predominantly found in cases of middle-aged female patients and occurs unilaterally. Cases of bilateral multiple forms in young males are extremely rare. Some cases of enlargement, metastasis and relapse have also been reported, so in the future, careful follow-up is required.
Key words: bilateral multiple lung nodule; sclerosing hemangioma; video-assisted thoracic surgery; young male
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